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过氧化氢酶和黏附素保守区二价疫苗治疗小鼠幽门螺杆菌感染
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【生物制药的论文】作者:白杨,陈丽,王继德,施理,唱韶红,张兆山,周殿元,张亚历【关键词】 幽门螺杆菌Immunzition treatment of Helicobacter pylori infection with two valence vaccine composed of catalase and adhesin conservation: An animal model study 【Abstract】 AIM: To investigate the effects of two valence vaccine consisting of Helicobacter pylori (H. pylori) catalase and adhesin conservation in the treatment of H. pylori infection in an H. pylori infected mouse model. METHODS: C57BL/6 mice infected with H. pylori were divided into seven groups. The mice of each group were immunized respectively by catalase and adhesin conservation (separately, 100 μg) plus CT (2 μg), catalase (100 μg) plus CT (2 μg), adhesin conservation (100 μg) plus CT (2 μg), catalase (100 μg), adhesin conservation (100 μg) and CT (2 μg), PBS orally once a week for four weeks. Four weeks after the last treatment, all animals were sacrificed and sto
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