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十一方药酒对大鼠皮肤深Ⅱ度烫伤创面愈合的影响
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【制药专业毕业论文】作者：覃学谦， 蔡丹昭， 陈洪涛， 韦艾凌【关键词】 十一方药酒；,,,烫伤；,,,创面愈合；,,羟脯氨酸摘要：目的探讨十一方药酒对大鼠深Ⅱ度烫伤创面愈合的 影响 。 方法 大鼠深Ⅱ度烫伤模型分5组，创面分别外用高、中、低剂量的十一方药酒, 以生理盐水为阴性对照, 湿润烧伤膏为阳性对照, 通过观察创面愈合时间，不同时间点创面愈合百分率和组织病 理学 变化，检测不同时间点创面组织羟脯氨酸水平， 研究 十一方药酒对大鼠深Ⅱ度烫伤创面愈合的影响。结果大鼠深Ⅱ度烫伤创面外用十一方药酒可以缩短愈合时间，提高创面愈合百分率，增加创面羟脯氨酸水平, 作用与湿润烧伤膏相当。结论 十一方药酒可增强胶原合成, 促进上皮细胞增殖, 加速烫伤创面愈合。
关键词：十一方药酒； 烫伤； 创面愈合； 羟脯氨酸
Abstract：ObjectiveTo observe the effects of Shi Yi Fang vinum on deep partial thickness burn wound in rats.Methods A model of deep partial thickness burn wound in rats was used. All wounded rats were divided into five groups, different concentration of Shi Yi Fang vinum was used, the wound healing time , the content of hydroxyproline, the rates of wound healing as well as the histopathological change of the wound tissues were examined at different time points post burn, so as to value the effects of Shi Yi Fang vinum on the hea
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